Hi Monesh, fascinating read! As someone with a grandmother suffering from Alzheimer's, and also having taken Professor Heller's property class this semester, I was interested in the overlap between these topics. The momentary component preventing medical advancements from being used by those who need them is heartbreaking. Another component of Alzheimer's that makes combatting it such a challenge is how often the disease is accompanied by Parkinson's and dementia. It's been really hard watching someone I love battle these degenerative conditions, and I am hopeful that Leqembi will provide a reasonably-priced solution in the future. It is unfortunate that current intellectual property rules and strategies place families between a rock and a hard place. While I try to remain hopeful, I feel this is the type of issue that may not be addressed without massive outcry. Those intent on keeping existing practices in place have massive amounts of money to lose if mechanisms such as evergreening are taken away. As a result, I worry they will remain in place until there is an even larger force pushing against them to oppose the ones supporting them. Thanks for sharing.

-Michael